Thiotepa classification
WebApr 1, 2024 · Thiotepa belongs to the group of medicines called alkylating agents. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by thiotepa, other effects will also occur. Some … WebFeb 17, 2024 · Excretion Urine (<2% of thiotepa dose; <11% of TEPA) Half-Life Elimination Terminal: Pediatrics (5 mg/kg IV dose): Thiotepa: 1.7 hours; TEPA: 4 hours Adults (20 mg to 250 mg/m 2 IV dose): Thiotepa: 1.4 to 3.7 hours; TEPA: 4.9 to 17.6 hours Protein Binding ~10% to 20% Use in Specific Populations Special Populations: Renal Function Impairment
Thiotepa classification
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WebN,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer … WebMedscape - Indication-specific dosing for tespa, Thioplex (thiotepa), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
WebSep 21, 2024 · Generic name: thiotepa [ THYE-oh-TEP-a ] Brand names: Tepadina, Thioplex Dosage form: injectable powder for injection (100 mg; 15 mg; 30 mg) Drug class: Alkylating agents Medically reviewed by Drugs.com on Sep 21, 2024. Written by Cerner Multum. Uses Warnings Before taking Side effects Interactions Dosage What is thiotepa? WebJan 4, 2024 · A comprehensive guide to side effects including common and rare side effects when taking Thiotepa (Thiotepa Injection) includes uses, warnings, and drug interactions. Drugs & Vitamins Drugs A-Z Generic Drugs A-Z Drugs …
WebNov 8, 2013 · Thiotepa and Pregnancy Tell your doctor if you are pregnant or plan to become pregnant. The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. This medication falls into category D. WebJan 4, 2024 · Thiotepa is a prescription medicine used to treat the symptoms of Bladder Cancer, Ovarian Cancers, Effusions, Leptomeningeal Metastases and High-dose IV Therapy for Bone Marrow Transplant. …
WebSep 21, 2024 · Generic name: thiotepa [ THYE-oh-TEP-a ] Brand names: Tepadina, Thioplex Dosage form: injectable powder for injection (100 mg; 15 mg; 30 mg) Drug class: Alkylating agents Medically reviewed by Drugs.com on Sep 21, 2024. Written by Cerner Multum. …
WebThiotepa suppresses cell growth and division and was introduced in 1953 for use in cancer chemotherapy to treat lymphoma and a vari-ety of solid and soft-tissue tumors. It was commonly used in cancer therapy until the early 1970s (only 3 kg of thiotepa was used in … swamp thing genreWebThiotepa is in a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in your body. How should this medicine be used? Thiotepa comes as a powder to be mixed with liquid to be injected intravenously (into a … swamp thing girlskinceuticals dermstoreWebSep 21, 2024 · Thiotepa is also known as: Tepadina, Thioplex Pregnancy Warnings Breastfeeding Warnings Thiotepa Pregnancy Warnings Animal studies have revealed evidence of embryolethality, mutagenicity, and teratogenicity. There are no controlled data in human pregnancy. skinceuticals distributorWeb2.1 Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) Acute toxicity, Oral (Category 2), H300 ... IARC: 1 - Group 1: Carcinogenic to humans (Thiotepa) NTP: Known - Known to be human carcinogen (Thiotepa) OSHA: No component of this product present at levels greater than or equal to 0.1% is on ... skinceuticals doctorsWebNov 1, 2024 · Thiotepa is a synthetic product with antitumor activity. The chemical name for Thiotepa is Tris(1-aziridinyl)phosphine sulfide. Thiotepa has the following structural formula: Thiotepa, USP has the molecular formula C 6 H 12 N 3 PS, and a molecular … swamp thing gifWebThiotepa is also being studied in the treatment of other types of cancer and as part of a regimen to prepare patients for bone marrow and stem cell transplants. More About Thiotepa. Definition from the NCI Drug Dictionary - Detailed scientific definition and other … swamp thing green hell #2 cancelled